I hit 'Update Graph' and nothing happens--what's wrong?
Do the calculators take into account treatment with drug _______?
The Outcome calculators are based on observed outcomes for United States cancer patients from 1987-2007, with greater weight given to more recent patients. Thus they do include data for any treatments used during this time period. However, the calculator may not reflect the full impact of treatments developed later in that time period, or not widely used until later in that period.
The breast cancer treatment calculator does take into account the specific drugs (or analogues) listed in the treatment selection menu, with the impact of the drugs calculated based on clinical trial results.
Do the calculators take into account differing surgical treatments?
The calculators are based on observed outcomes for cancer patients from 1987-2007, with greater weight given to more recent patients. Thus they are based on data including all surgical treatments used during this time period, and the relative frequency of a given surgical procedure for a given tumor type.
How do I get a mortality estimate which excludes the chance of non-cancer death?
If an age of 0 is entered, the calculators will ignore any chance of non-cancer death
How do I get a mortality estimate for a patient whose cancer has metastasized to one or more distant sites?
Our calculators are designed to provide predictions for cancers that have no presently detected distant metastases. Thus the projections do not apply to cancers that are already known to be metastatic.
How has the accuracy of these calculators been verified?
All calculators have been verified against cancer patients diagnosed between 1987-2007 in the United States Surveillance, Epidemiology and End-Results database. The breast cancer and melanoma calculators have also been validated against a database of ~30,000 breast cancer and ~7,000 melanoma patients seen at Partners Hospitals
How accurate are the projections?
When verifying the accuracy of the calculators against independent data sets (using different patients than the patients that the model parameters were dervied from) the mean and median error across patient stratifications are typically ~2% Thus, if a calculator outputs a projected 15-year mortality of 16%, the actual value may in fact vary between 14-18%. The accuracy is generally higher for the most common types and sizes of tumors, and lower for the rarer and the most advanced tumors. For details, see our technical reports
I don't see an answer to my question above
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